Concepedia

Concept

ligand-based drug design

Parents

358

Publications

25.5K

Citations

1.3K

Authors

437

Institutions

About

Ligand-based drug design is a computational approach within pharmaceutical research that focuses on identifying and optimizing potential drug candidates by analyzing the chemical and structural properties of known active ligands, inferring the essential molecular features required for biological activity without explicit knowledge of the target structure. This methodology is significant for drug discovery when target structural information is unavailable, providing valuable insights into pharmacophores and structure-activity relationships to guide the design of novel compounds.

Top Authors

Rankings shown are based on concept H-Index.

GS
AC

University of Zurich

AD

University of Maryland, Baltimore

EP

Goethe University Frankfurt

PS

ETH Zurich

Top Institutions

Rankings shown are based on concept H-Index.

Goethe University Frankfurt

Frankfurt am Main, Germany

University of Zurich

Zurich, Switzerland

ETH Zurich

Zurich, Switzerland

New York, United States